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Synchill: All Natural Horse Calming Supplement

SynNutra Equine Founder, Edwin Simpson, DVM, discusses best horse calming supplement on the market today..

Learn what makes these products unique.

Hear a testimonial from International Show Jumping star, Ashlee Bond and why she believes it's the most exciting product in her barn.

SynChill, The Natural Horse Calming Supplement Developed by an equine veterinarian, SynChill is an all-natural feed supplement, formulated to calm nervous horses.

SynNutra, Inc., the nutraceutical company founded with a mind to both safely and effectively promote complete equine wellness, offers SynChill— a palatable, drug-free, oral gel that produces a sense of relaxation in your horse when administered in advance of a stressful event. In addition to its calming effects, SynChill allows horses to both focus and perform confidently and securely; with the complete mental clarity and physical ability that sedatives and tranquilizers simply cannot offer.

Initially tested in young Thoroughbred race horses, SynChill contains a totally unique blend of natural biochemical substances that repeatedly prove effective in reducing anxiety and calming horses even in the fast-paced environment of the race track. These calm horses can focus and perform at the highest level.

What makes SynChill the best horse calming supplement? SynChill is composed of the natural brain chemical, 5-HTP (5-Hydroxytryptophan); a totally unique offering in the world of equine calming supplements. 5-HTP is the precursor to serotonin, the hormone widely recognized as a natural antidepressant, and is critical to the horse calming properties of SynChill.

Some commonly known vitamin pastes and powders show a negligible response to equine stress, and the tryptophan products alone do not have the ability to cross the blood-brain barrier, rendering them virtually useless in decreasing anxiety unless used at very high, unnatural levels.

Dispensed in handy, single-dose syringes, SynChill is a pleasantly sweet-tasting, odor-free, clear gel. Composed solely of endogenous ingredients, SynChill is not a drug, and contains no banned substances. SynChill oral gel is a proprietary blend of 5-HTP, Vitamin B6, and melatonin that took years to develop and perfect.

Unlike typical tryptophan-based supplements, SynChill is the only one that contains 5-HTP (5-hydroxytryptophan) — a game-changer among equine calming products. An important amino acid, 5-HTP crosses the blood-brain barrier (as an active ingredient) to become a key player in the formation of serotonin; one of the body’s widely recognized “feel good” hormones. Vitamin B6 promotes the conversion of 5-HTP to serotonin, further enhancing its natural horse calming effects. Melatonin increases and intensifies the production and maintenance of serotonin, complementing the stress-reducing properties of both hormones. Please see the diagram below for a graphic explanation.

5-htp makes SynChill a better horse calming supplement than those containing Tryptophan

Horse Calming Supplements To become 5-HTP, an active ingredient, tryptophan must first bemetabolized by the liver to freely cross the blood-brain barrier.

SynChill contains 5-HTP which crosses the blood barrier freely. Vitamin B-6 promotes the conversion 5-HTP to serotonin which is the active horse calming agent.


SynNutra Equine is a business with roots firmly planted in equine veterinary medicine. Their products are formulated, developed and tested in their own California facility so they can ensure that their clients receive products they can trust every time. After years of extensive research and consultation with scientists, pharmacologists and herbologists, SynNutra Equine has developed an approach to equine health that combines the benefits of both western science and eastern medicine. At SynNutra Equine, they are as committed to and as serious about your horse’s health and performance as you are!

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